Patient Perceptions on the Use of AI in Creating Clinical Research Documents: Survey Study
By CISCRP Staff|Jun 25, 2026
By CISCRP Staff|Jun 25, 2026
By Kim Edwards, Samuel Entwisle, Zack Fey, Hana Do, Art Gertel, Annick de Bruin, and Kenneth Getz.
The use of artificial intelligence (AI) by pharmaceutical companies and other organizations for preparing patient-facing documents reporting results of clinical research is becoming more common. This raises concerns about whether the accuracy and quality of these documents could be affected, as well as the potential impact on patient perceptions and trust. Accurate and trustworthy information is critical to health care decision-making. Little is known about patient perceptions of AI-generated content.
Drawing on a large international survey, the article reveals that patients are increasingly familiar with and even optimistic about AI’s capabilities, yet they remain deeply reliant on human expertise to ensure accuracy, clarity, and credibility. The findings highlight not only the promise of AI to improve how complex medical information is shared, but also the essential role of transparency and human oversight in preserving trust.
Most respondents had prior experience with AI and believed it can improve document quality, such as reducing grammar and data errors.
Trust was lowest for fully AI-generated documents and highest when humans created or oversaw them, with 95% of participants emphasizing the importance of human review.
A majority of respondents considered it important for organizations to clearly disclose when AI is used in clinical research communications.